People may depend on the drug to achieve positive feelings, neglecting aspects of their daily lives to acquire or use it. There is little information available about the pharmacology of hallucinogenic 2Cs. It has been shown that 2Cs have an affinity for 5-HT2 and alpha-adrenergic receptors, but these compounds can be either agonists or antagonists, which is dependent on the specific receptor subtype 12–14. It is possible to create new hallucinogenic 2Cs by placing different substituents on the aromatic ring at positions 2, 4, or 5 5, 16.

Lamotrigine and olanzapine were up-titrated to 50 mg twice a day and 5 mg at night, respectively. With adherence, the patient’s mood improved significantly, and she experienced notable reductions in irritability and agitation. Her final diagnosis at discharge was bipolar I disorder, a most recent episode of depression with mixed features, severe.

In the Netherlands, 2C-B became a list I substance of the Opium Law despite no health incidents occurring. Following the ban, other phenethylamines were sold in place of 2C-B until the Netherlands became the first country in the world to ban 2C-I, 2C-T-2 and 2C-T-7 alongside 2C-B. 2C-B is controlled in Australia and on the list of substances subject to import and export controls (Appendix B). It was placed on Schedule One of the Drugs Misuse and Trafficking Act when it first came to notice in 1994, when in a showcase legal battle chemist R.

If you or someone you know is struggling with 2C dependence or any substance use disorder, then it is important to seek treatment via a dedicated rehab specialist. Visit our rehab directory today to find an addiction treatment center near you. 2C drugs are a group of synthetic psychedelic drugs first synthesized in the 1970s as a therapy aid. 2C drugs come in multiple forms including 2C-E, 2C-I, 2CT-7, and 2CB which is the most commonly used version available today. In low doses, 2C-E can act as a stimulant, causing feelings of alertness and intensifying a person’s senses. In higher doses, usually greater than 10 milligrams, the drug has significant hallucinogenic effects.

“Tusi” is often referred to as “pink cocaine” on the streets and is a dangerous new synthetic drug that is growing in popularity across the United States, particularly among young adults. As a powerful mixture of various psychoactive ingredients, Tusi is most popular in the club scene and as a party drug and is known for its mind-altering hallucinogenic effects. Many users feel that 2C-P is the strongest of all the 2C-X drugs. It often gives a very intense experience with extremely vivid visuals. If you haven’t tried 2C-X drugs before, it’s not recommended that you start with 2C-P.

Alexander Shulgin: The Godfather of Psychedelics

The effects of 2C-E typically last for eight to 12 hours, but some 2C drugs can last for 24 hours or longer. Snorting the drugs causes a more rapid onset of effects than swallowing them does. In the 1980s and 1990s, before they were made illegal, 2C drugs were sometimes sold at adult bookstores and nightclubs as sexual enhancement products. The high from 2C drugs is said to intensify emotion, enhance the senses and make people feel more in tune with their surroundings. It’s unclear whether 2C drugs are addictive, but preliminary research suggests the substances are unlikely to cause addiction or physical dependence. Further research is needed before scientists can reach a definitive answer.

What Are 2C and 2C-B Drugs?

There is some concern that hyperthermia occurring in excited delirium results from specific dopamine transport derangements as occurs in neuroleptic malignant syndrome 47. Therefore, using neuroleptics could be argued as contraindicated. However, as mentioned previously, what is the drug 2c neuroleptics have a long history of safe use in undifferentiated agitation, and it is felt their benefit of use outweighs this risk. Studies examining the pharmacokinetics and pharmacodynamics of 2Cs are limited.

What Are the Most Popular 2C-X Drugs?

It is always a good idea to test your substances before you use them. About an hour after consuming it, 2C-B tends to start taking effect. Snorting 2C-B brings on its effects much faster and can prolong the experience for up to 12 hours. It’s not clear whether or not microdoses of 2C-B are safe long term.

Mixing drugs

Our body isn’t dependent on the substance, but we still seek it out in order to feel a certain way. We can also become behaviorally addicted to gambling, sex, masturbation, or shopping. Compulsive use of any substance would be an example of having an unhealthy relationship with the substance.

Drugs in the 2C family usually come in the form of capsules or tablets that are swallowed or a powder form that is snorted. The content on RehabNet.com is intended purely for informational and educational purposes. The information available on RehabNet.com shouldn’t be utilized as a means to diagnose or treat health issues or diseases. If you think you might be facing a health challenge, please consult with a healthcare professional. The creators, editors, and contributors of this website are not liable for any purported damage or adverse effect, directly or indirectly, resulting from the information presented on this site.

• Neuroleptics can be used in the setting of hallucinogen-induced agitation, although some controversy exists regarding their use.
• Scales are cheap (less than $20) and could mean the difference between having a positive experience and ending up in a hospital.
• This may explain why the drugs are popular among young people who frequent music festivals and the club scene.
• Lower doses of 2C-B are the most similar to MDMA for creating a greater sense of connectedness with the people around you.
• As psychedelics tend to increase one’s heart rate, they also pose a higher risk of complicating preexisting heart conditions.

The United States is experiencing a synthetic opioid epidemic that has claimed thousands of lives due to street drugs being adulterated with other drugs, such as fentanyl. Fentanyl is an incredibly powerful and deadly narcotic, with doses as low as two milligrams (a dose so small it could fit on the tip of a pencil) being potentially deadly. While it is never recommended to consume any illicit substances, it is critical that you or the people you know test any drugs you may ingest for fentanyl. Several non-profit harm reduction organizations, such as DanceSafe, offer fentanyl testing strips and at-home drug testing kits. Because 2C-B is illegal and produced in secret laboratories, these illicit drugs are often laced with other substances, causing significant physical and mental risks.

• While hallucinogens are not typically as addictive as other types of drugs, the stimulant aspect of Tusi can make it highly addictive.
• Multiple names under which 2C drugs are sold were identified and tabulated.
• Mixing drugs is always risky but some mixtures are more dangerous than others.
• In higher doses, it tends to be more psychedelic with intense visuals.

Both 2C-B and mescaline are thought of as being “gentle” when compared to other psychedelics and the visuals are very similar between the two. 2C-B is more stimulating than mescaline and has much less “headspace.” Headspace refers to the introspective and existential thoughts that accompany the psychedelic experience. Lower doses (5 mg) resemble Adderall or MDMA and don’t produce strong visuals. Most of them were invented around the same time by Alexander Shulgin and documented in one of his books PiHKAL.

Tusi was first found in Colombia and throughout Latin America around 2010 but has since spread to other areas of the world, including throughout the United States. Tusi is frequently marketed under the name “pink cocaine.” This name and branding are misleading, however, as Tusi rarely ever actually contains any cocaine. “Tusi”, on the other hand, although its name sounds similar to “2C” when pronounced aloud, rarely contains any of the 2C drugs. By participating in these programmes, individuals recovering from 2C-B addiction can receive the support, guidance, and tools they need to overcome their addiction and rebuild their lives.